Editor-in-Chief:
Courtney M. Townsend, Jr., MD, Professor and John Woods Harris Distinguised Chairman, Department of Surgery, The University of Texas Medical Branch, Galveston, Texas

Associate Editors:
R. Daniel Beauchamp, MD, The John L. Sawyers Professor of Surgery, Professor of Cell Biology, Chief, Division of Surgical Oncology, Department of Surgery; Associate Director of Clinical Programs, Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville Tennessee
B. Mark Evers, MD , Professor and Robertson-Poth Distinguished Chair in General Surgery, Department of Surgery, The University of Texas Medical Branch, Galveston, Texas
Keneth L. Mattox, MD, Professor and Vice Chairman, Department of Surgery, Baylor College of Medicine; Chief of Staff, Chief of Surgery, Ben Taub General Hospital, Houston, Texas

The new 16 ^th edition of this classic text continues to provide surgery residents and practicing general surgeons with the most comprehensive information available in surgery. This exhaustive revision includes more than 1,500 illustrations, 1,800 of the most recent references available in surgery, and the most up-to-date advances in cardiothoracic surgery, neurosurgery, plastic and maxillofacial surgery, pediatric surgery, hand surgery, orthopedics, gynecology, and urology. Content also includes the historical and developmental aspects of surgical practice and the anatomical, pathological, physiological, biochemical and molecular basis of several disorders.

Townsend and a dynamic new panel of expert authors and contributors have closely aligned content with the American Board of Surgery recommendations for general surgery programs, making this new edition even more user-friendly. The result is a comprehensive text providing the scientific underpinnings of surgery in a clinically useful format.

Features

• Emphasizes the principles of molecular biology fundamental to surgical practice.
• Reviews the basic features of tumor biology, including a thorough review of specific tumor markers, and diagnosis and therapy of individual neoplasms.
• Provides a complete review of transplantion addressing immunosuppression, organ preservation, individual transplantable organs and tissues, and the emergence of xenotransplantation.
• Provides surgical solutions to gastrointestinal problems affecting the esophagus, stomach, duodenum, small intestine, colon and rectum, as well as the liver, biliary system and pancreas.
• Reviews surgical management techniques for the arterial and venous systems, with detailed chapters on anatomy, physiology, arterial susbsitutes, aneurysms, thromboembolic disease, arterial injuries, and much more.
• Explores cardiac disorders and the use of cardiac catheterization, radionuclide angiocardiography, scanning techniques, echocardiography, and minimally invasive therapeutic approaches.
• Emphasizes minimally invasive surgeries using laparoscopic and thoracoscopic techniques in words and pictures.
• More than 100 new expert authors lend fresh perspectives on the latest techniques.
• Eleven entirely new chapters, including : The Role of Cytokines as Mediators of the Inflammatory Response, Molecular and Cell Biology, Surgical Critical Care, Respiratory Failure, Endocrine Pancreas, Pain Management and Conscious Sedation, Surgery in Geriatric Patients, Surgery in Obese Patients, and Principles of Minimally Invasive Surgery.