Nathan, D.: NATHAN & OSKI'S  HEMATOLOGY OF INFANCY AND CHILDHOOD, 6th Ed. - June 2003 - 337,00 € - 2060 Pag. - 1200 Illus.
David G. Nathan MD, President Emeritus, Dana-Farber Cancer Institue, Robert A. Stranahan Distinguished Professor of Pediatrics, Harvard Medical School, Boston, MA  
Stuart H. Orkin MD, Chief, Division of Hematology & Oncology, Children's Hospital, Boston, MA  
A. Thomas Look MD, Division of Pediatrics, Dana Farber Cancer Institute, Boston, MA  
David Ginsburg MD, Professor of Medicine, Howard Hughs Medical Institute, University of Michigan School of Medicine, Ann Arbor, MI  
 
Presenting the New Edition of the classic reference on paediatric haematology and oncology. Comprehensively revised and updated, it continues to integrate lucid reviews of the pathophysiology of disease with detailed clinical guidance on its diagnosis and management. Drs. Nathan and Orkin - joined by two new co-editors and an outstanding team of authors - worked tirelessly to ensure that all the latest scientific advances appear in the 6th Edition.  
 
Reviews
 
"The bible of pediatric hematology. There simply is no other book that approaches either the breadth or the depth of content for the specialist in pediatric hematology."  
-- The New England Journal of Medicine  
 

Features
  • Nearly 50% of the chapters have been rewritten for the 6th Edition; the remaining chapters have been thoroughly revised and updated
  • Two new co-editors, Dr. Thomas Look and Dr. David Ginsberg, who contribute their expertise to the neoplastic diseases and coagulation sections
  • Important new coverage of transfusion medicine, stem cell transplantation protocols, the haematological manifestations of paediatric AIDS/HIV, and more
  • The recently codified WHO classification for all lymphomas and leukemias

Contents
 
History 
1. Pediatric Hematology in Historical Perspective (Nathan)  
Neonatal Hematology  
2. The Neonatal Erythrocyte and Its Disorders (Brugnara & Platt)  
3. Immune Hemolytic Disease (Liley)  
4. Disorders of Bilirubin Metabolism (Whitington & Alonso)  
5. Developmental Hemostasis: Relevance to Newborns and Infants (Monagle)  
Bone Marrow Failure  
6. The Anatomy and Physiology of Hematopoiesis (Sieff)  
7. Acquired Aplastic Anemias (Shimamura & Guinan)  
8. Inherited Bone Marrow Failure Syndromes (Alter)  
9. Principles of Bone Marrow and Stem Cell Transplantation (Lehmann, Haining, & Guinan)  
Disorders of Erythrocyte Production  
10. A Diagnostic Approach to the Anemic Patient (Brugnara & Nathan)  
11. Megaloblastic Anemia (Neufeld)  
12. Disorders of Iron Metabolism and Sideroblastic Anemia (Andrews)  
13. The Porphyrias (Sassa & Kappas)  
Hemolytic Anemias  
14. Autoimmune Hemolytic Anemia (Ware)  
15. Disorders of the Erythrocyte Membrane (Gallagher)  
16. Pyruvate Kinase Deficiency and Disorders of Glycolysis (Mentzer)  
17. Glucose-6-Phosphate Dehydrogenase Deficiency and Hemolytic Anemia (Luzzatto)  
Disorders of Hemoglobin  
18. Human Hemoglobins: Normal and Abnormal (Nagel)  
19. Sickle Cell Disease (Dover & Platt)  
20. The Thalassemias (Orkin & Nathan)  
The Phagocyte System  
21. The Phagocyte System and Disorders of Granulopoiesis and Granulocyte Function (Dinauer)  
The Immune System  
22. Cell-Mediated and Humoral Immunity and the Regulation of Immune Responses (Bierer)  
23. Primary Immunodeficiency Diseases (Bonilla & Geha)  
Oncology 
24. Epidemiology of Leukemia in Childhood (Bhatia & Robison)  
25. Chromosomal Abnormalities in Childhood Hematological Malignant Diseases (Olney, Gozzetti, & Rowley)  
26. Acute Lymphoblastic Leukemia (Sallan & Silverman)  
27. Myeloid Leukemias, Myelodysplastic Syndrome and Other Myeloproliferative Disorders (Look)  
28. Infant Leukemias (Reaman)  
29. Molecular Biology of Hematologic Malignancies (Golub)  
30. Minimal Residual Leukemia (Gribben)  
31. Pharmacology of Antineoplastic Agents and Multidrug Resistance (Berg & Poplack)  
32. Cell, Cytokine, Monoclonal Antibody and Gene Therapy (Sondel & DeSantes)  
33. Childhood Lymphomas and Lymphadenopathy (Link)  
34. Lymphohistiocytic Disorders (Sullivan)  
Storage Diseases  
35. Storage Diseases of the Reticuloendothelial System (Kolodny)  
Hemostasis 
36. Blood Platelets in the Vessel Wall (Handin)  
37. Blood Coagulation (Esmon)  
38. The Molecular Basis of Fibrinolysis (Hajjar)  
39. Clinical and Laboratory Approach to the Bleeding Patient (Lusher)  
40. Inherited Platelet Disorders (Poncz)  
41. Hemophilia and von Willebrand Disease (Montgomery)  
42. Rare Hereditary Coagulation Factor Abnormalities (Bauer)  
43. Inherited Disorders of Thrombosis and Fibrinolysis (Neufeld & Bauer)  
44. Acquired Platelet Disorders (Wilson)  
45. Acquired Disorders of Hemostasis (Monagle)  
Supportive Therapy  
46. Psychologic Aspects of Leukemia and Other Hematologic Disorders (Jelalian, Boergers, Spirito, & Sourkes)  
47. Infectious Complications in Children with Hematologic Disorders (Koh & Pizzo)  
48. Transfusion Support (Silberstein, Benjamin, Sloan, Webb, & Friedman)  
49. Hematologic Manifestations of Systemic Diseases (Ezekowitz)  
50. Hematologic Manifestations of Systemic Diseases in Children of the Developing World (Weatherall & Kwiatkowski)  
Appendices 
Reference Values in Infancy and Childhood