Previous editions of this book have been known as "the bible" of pediatric nephrology. New to the fourth edition is material on molecular biology and management of end-stage renal failure. The latest version is not only more succinct, but also more oriented to practical clinical pediatric nephrology. By blending the latest bench research with advances in clinical practice procedures for an audience of pediatric sub-specialists, this text becomes a complete source book for anyone dealing with pediatric renal disease. The Lancet called the third edition "a valuable reference book for paediatricians, paediatric surgeons, and adult nephrologists, all of whom come across problems addressed in this book"