Thomas D. Dubose, Jr, MD, Chair, Dept. of Internal Medicine, University of Kansas Medical Center, Kansas City, KS  
 
Lee Hamm, MD, Section of Nephrology, Tulane University Medical Center, New Orleans, LA  

 
 
This companion to Brenner and Rector's The Kidney offers a concise, practical approach to acid-base and electrolyte disorders, emphasizing pathophysiology and its link to a logical diagnostic approach in treating these disorders. Unlike other traditional textbooks on the subject, Acid/Base and Electrolyte Disorders focuses less on physiological and pathophysiological concepts and more on providing specific recommendations for therapy and patient care - resulting in an excellent clinical resource that is also an ideal core curriculum or exam review. Many of the topics in this book are not covered in any other resource, including acid-base and electrolyte disorders in the critical care setting. In addition, recent advances in fast-developing areas such as genetic and molecular biology are discussed in detail.  

 

Features
  • Emphasizes acid-base and electrolyte abnormalities in the critical care setting - a topic not fully covered in any other resource.
  • Includes the most up-to-date information on hot topics such as molecular biology and genetics of tubular transport abnormalities, hypertension, and calcium, sodium, and potassium homeostasis.
  • Authors and contributors are experts in their field, providing the most authoritative information available.
  • Figures and tables throughout the book help clarify important concepts.
  • A detailed reference list for each chapter directs the reader to sources for further information, and readers are referred back to Brenner and Rector's The Kidney for complete discussions the complex physiology of certain disorders.

 
Contents
 
I. Acid Base Disorders  
  1. Regulation of whole body acid-base balance
  2. Urinary acidification
  3. Diagnosis of simple and mixed disorders
  4. Metabolic acidosis
  5. Ketoacidosis
  6. Lactic acidosis
  7. Metabolic alkalosis
  8. Respiratory acidosis
  9. Respiratory alkalosis
  10. Acid-base disorders in the critical care setting
  11. Renal tubular acidosis
  12. The acidosis of CRF
  13.  
 
II. Water  
  1. Cell biology of vasopressin and the aquaporins
  2. Hyponatremia
  3. Hypernatremia and the polyuric disorders
  4.  
 
III. Electrolytes: Sodium  
  1. Sodium transport in the kidney
  2. The renin-angiotensin-aldosterone system
  3. The edematous disorders
  4. Salt washing
  5. Genetic disorders of renal electrolyte transport
  6. Electrolyte abnormalities in the ICU
  7.  
 
IV. Electrolytes: Potassium  
  1. Regulation of renal potassium transport
  2. Hypokalemia
  3. Hyperkalemia
  4. Aldosterone deficiency and resistance
 
V. Electrolytes: Divalent Ions  
 
1. Renal regulation of calcium, magnesium, and phosphorus  
2. Abnormal calcium and magnesium metabolism  
3. Hypophosphatemia and hyperphosphatemia  
4. Idiopathic hypercalciuria and renal stone disease