Adkinson; F.: MIDDLETON'S ALLERGY 6th Ed. - August 2003 - 420,00 € -

 

This new 6 th Edition carries on the long-standing tradition of excellence that has earned MIDDLETON'S ALLERGY: Principles and Practice a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on relevant animal experimentation, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management . 
 
An international group of editors and contributors , ranking amongst the world's most noted authorities in allergy, have comprehensively updated this new edition to incorporate all of the very latest advances in scientific and clinical knowledge.  
 
Also now included FREE is the Adkinson edition, a website that gives you:   
  • All of book's contents online, fully searchable
  • Regular updates to the content, keeping you contantly up-to-date
  • A complete library of easily downloadable electronic images
  • Links to key allergy websites
  • Patients handouts... and more!

 

Reviews
 
"Excellent...Required reading for anyone training or practicing as an allergy-immunology subspecialist. It provides practical information for the dermatologist, pediatrician, pulmonologist, internist, gynecologist, and any other primary care physician encountering medical disorders of allergic-immunologic origin."  
-- JAMA  


Features
 
Presents fresh perspectives from 3 new editors and a multitude of new contributors.  
Delivers a truly international perspective on every aspect of allergic disease--putting global "best practices" at your fingertips.  
Offers brand-new coverage of aerobiology of outdoor allergens indoor and outdoor air pollution allergy vaccines antigen presentation and immunoregulation and many other topics!  
 
You'll also find. . .  
Ongoing content updates through the enclosed website.  
Many of the illustrations from the 2-volume set in downloadable format.  
Links to relevant web sites.  
Patient education materials.  
And much more!  
 

What's New
  • Presents the very latest information on neuronal control of airway function and airway inflammation antigen presentation and processing genetics of allergic disease and asthma signal transduction events biology of airway smooth muscle cells immunopathology of allergic airway inflammation animal models of asthma structure and function of allergens theophylline and phosphodiesterase inhibitors early childhood correlates of allergic disease allergenic vaccines and much more!
  • Provides a truly international perspective on every aspect of the subject, with contributions by many more authors from outside the US than ever before.
  • Lists today's most useful website addresses relevant to science and practice.
  • Offers a new, more reader-friendly layout for easier reference.

 
Contents
 
 
Section A: Immunology  
1: The Immune System: An Overview  
2: Molecular Biology and Genetic Engineering  
3: Principles and Application of Genetics  
4: Genetics of Allergic Disease and Asthma  
5: Immunoglobulin Structure and Function  
6: The Complement System  
7: Synthesis and Regulation of Immunoglobulin E  
8: Signal Transduction  
9: Cellular Adhesion in Inflammation  
10: Cytokines in Allergic Inflammation  
11: Chemokines in Cell Movement and Inflammation  
12: Antigen Presentation and Immunoregulation  
13: Mast Cell-Derived Mediators  
14: Lipid Mediators of Hypersensitivity and Inflammation  
15: Neuronal Control of Airway Function in Allergy  
16: Biochemical Events in Basophil or Mast Cell Activation and Mediator Release  
17: Biology of Lymphocytes  
18: Biology and Role of Neutrophils in Asthma  
19: Biology of Eosinophils  
20: Biology of Mast Cells  
21: Biology of Basophils  
22: Biology of Monocytes and Macrophages  
23: Biology of Epithelial Cells  
24: Biology of Endothelial Cells  
25: Biology of Airway Smooth Muscle Cells  
26: Apoptosis of Inflammatory Cells  
27: Delayed-Type Hypersensitivity and Cellular Immunity: Effector/Regulator Molecules and Mechanisms  
28: Allergic Inflammation: Initiation, Progression, and Resolution  
29: Animal Models of Asthma  
30: Pathophysiology of Allergic Inflammation  
31: Immunopathology of Allergic Airway Inflammation  
 
Section B Aerobiology and Diagnosis of Allergy  
 
32: Air Pollution: Indoor and Outdoor  
33: Aerobiology Outdoor Allergens  
34: Indoor Allergens  
35: Preparation and Standardization of Allergen Extracts  
36: Allergen Structure and Function  
37: Methods in Laboratory Immunology  
38: In Vivo Methods for Study of Allergy: Skin Tests, Techniques, and Interpretation  
39: Nasal Provocation Testing  
40: Bronchial Challenge Testing  
 
Section C Physiology  
 
41: Structural and Functional Cutaneous Immunology  
42: Immunologic and Nonimmunologic Lung Defense Mechanisms  
43: Structure and Function of Airway Smooth Muscles  
44: Development, Structure, and Physiology in Normal and Asthmatic Lung  
45: Airway Mucus and the Mucociliary System  
46: Aerosols  
47: Anatomy and Physiology of the Nose and Control of Nasal Airflow  
 
Section D Pharmacology  
 
48: Principles of Pharmacotherapeutics  
49: Beta-Adrenergic Agonists  
50: Theophylline and Phosphodiesterase Inhibitors  
51: Antihistamines  
52:Glucocorticosteroids A) Mechanisms of Action in Allergic Diseases B) Clinical Use  
53: The Chromones: Cromolyn Sodium and Nedocromil Sodium  
54: Cholinergic Mechanisms and Anticholinergic Therapy in Respiratory Diseases  
55: Antileukotriene Therapy in Asthma  
56: Immunomodulators  
 
Section E Clinical Science  
 
57: Cell-Mediated Immunity in Health and Disease  
58: Immune Complexes and Allergic Disease  
59: Primary Immunodeficiency Diseases  
60: Approach to the Patient with Recurrent Infections  
61: Immunology of HIV Infection and Its Relationship to Allergic Diseases  
62: Clinical Significance of IgE  
63: Eosinophilia and Easinophil-Related Disorders  
64: Epidemiology of Asthma and Allergic Diseases  
65: Allergic Disease in Childhood A) Natural History, Development, and Prevention B) Early Childhood Correlates of Allergic Disease  
66: Asthma: Definition and of Allergic Disease in Pathogenesis  
67: Pathology of Asthma Compared with Chronic Obstructive Pulmonary Disease  
68: Asthma in Infancy and Childhood  
69: Asthma in Adults: Evaluation and Management  
70: Asthma Guidelines and Outcomes  
71: Asthma and Allergic Diseases During Pregnancy  
72: Exercise-Induced Airway Narrowing  
73: Occupational Asthma  
74: Allergic Bronchopulmonary Aspergillosis  
75: Hypersensitivity Pneumonitis  
76: Allergic and Nonallergic Rhinitis  
77: Endoscopy of the Upper Airway  
78: Nasal Polyps and Sinusitis  
79: Otitis Media  
80: Immunotherapy for Inhalant Allergens  
81: Insect Allergy  
82: Natural Rubber Latex Allergy  
83: Anaphylaxis and Anaphylactoid Reactions  
84: Mastocytosis Syndromes  
85: Urticaria and Angioedema  
86: Atopic Dermatitis  
87: Contact Dermatitis  
88: Allergic and Immunologic Disorders of the Eye  
89: Adverse Reactions to Foods  
90: Adverse Reactions to Food and Drug Additives  
91: Adverse Reactions to Vaccines  
92: Drug Allergy  
Appendix A Chemokines  
Appendix BAdhesion Molecules  
Appendix C Leukocytes  
Appendix D Internet sites