Abelson: Allergic Diseases of the Eye

Mark B. Abelson, MD, Clinical Associate Professor of Ophthalmology, Harvard Medical School, Boston, MA; Ophthalmic Research Associates, North Andover, MA

This valuable reference provides comprehensive coverage of the basic mechanisms and pathophysiology of ocular allergies and details a broad range of the latest therapeutic agents and their appropriate clinical applications.
 

  • Presents complete clinical descriptions of ocular allergic diseases and their multitude of manifestations, including the most commonly affected age groups and the various degrees of severity.
  • Facilitates the differential diagnosis of all external ocular diseases with clear descriptions of the clinical manifestations of ocular allergic conditions.
  • Describes the functions of each of the critical cell types involved in allergy, including mast cells, eosinophils, and lymphocytes.
  • Explains the roles of various mediators, including interleukins, adhesion molecules, cytokines, and chemokines.
  • Lists current therapeutic agents by class and reviews their modes of activity in relevant clinical studies.

    • Includes artistic renditions of various clinical conditions which illustrate and clarify the different manifestations.

    Contents:

    Genetic and Environmental Factors in Ocular Allergy
    Functional Anatomy of the Human Conjunctiva
    Mast Cells and Allergic Inflammation in the Eye
    T Lymphocytes
    Eosinophils
    Polymorphonuclear Leukocytes
    Basophils
    Histamine
    Immunoglobulins and Allergic Inflammation in the Eye
    Cytokines in the Ocular Environment
    Platelet Activating Factor
    Leukotrienes
    Prostaglandins
    Mast Cell Tryptase: Its Role in Ocular Allergic Inflammation
    Acute Allergic Conjunctivitis
    Atopic Keratoconjunctivitis
    Giant Papillary Conjunctivitis
    Marginal Infiltrates of the Cornea in Allergic Disease of the Eye
    Contact Lens-Induced Allergic Reactions
    Medicamentosa
    Vernal Keratoconjunctivitis
    Drug Pharmacokinetics
    Antihistamines and Antihistamine/Vascoconstrictor Combinations
    Corticosteroids
    Nonsteroidal Anti-Inflammatory Drugs
    Mast Cell Stabilizers
    Vasoconstrictors
    Novel Treatments and Targets